COVID Testing Kits
AdipoGen SARS-CoV-2 Inhibitor Screening Kit (96 wells)
Screening Assay: To screen compounds that inhibit the binding of the viral protein SARS-CoV-2 Spike Protein (RBD) to its human receptor ACE2. SARS-CoV-2 contains 4 structural proteins, including Envelope (E), Membrane (M), Nucleocapsid (N) and Spike (S), which is a transmembrane protein, composed of two subunits S1 and S2. The S1 subunit contains a receptor binding domain (RBD), which binds to the cell surface receptor Angiotensin-Converting Enzyme 2 (ACE2) present at the surface of epithelial cells, causing mainly infection of human respiratory cells. The SARS-CoV-2 Inhibitor Screening Kit contains key reagents required to facilitate identification of SARS-CoV-2 inhibitors, based on the binding of the RBD of the Spike S protein from SARS-CoV-2 to its human receptor ACE2. This assay allows to identify and characterize the effect of different inhibitory molecules including antibodies or chemicals on the prevention of binding of SARS-CoV-2 virus to any ACE2-expressing cells.
AdipoGen SARS-CoV-2 Neutralizing Antibodies Detection Kit (96 wells)
SARS-CoV-2 contains 4 structural proteins, including Envelope (E), Membrane (M), Nucleocapsid (N) and Spike (S), which is a transmembrane protein, composed of two subunits S1 and S2. The S1 subunit contains a receptor binding domain (RBD), which binds to the cell surface receptor Angiotensin-Converting Enzyme 2 (ACE2) present at the surface of epithelial cells, causing mainly infection of human respiratory cells.The SARS-CoV-2 Neutralizing Antibodies Detection Kit contains key reagents required to test the presence of functional neutralizing antibodies against SARS-CoV-2 present in the serum or plasma. It is an easy and fast alternative to the classical neutralization assay using Vero E6 cells. This Detection Kit is based on a colorimetric reaction, which measures the binding of the RBD of the Spike S protein from SARS-CoV-2 to its human receptor ACE2.
Zymo Research Corporation Quick SARS-CoV-2 rRT-PCR Kit, 1,000 rxns
Quick SARS-CoV-2 rRT-PCR Kit is a real-time RT-PCR test intended for the qualitative detection of nucleic acids from SARS-CoV-2 in upper respiratory specimens (such as nasal, nasopharyngeal, mid-turbinate or oropharyngeal swabs), and lower respiratory specimens (such as sputum, tracheal aspirates, and bronchoalveolar lavage) from patients suspected of COVID-19 by their healthcare provider.The Quick SARS-CoV-2 rRT-PCR Kit is intended for use by qualified clinical laboratory personnel specifically instructed and trained in the techniques of real-time RT-PCR assays.The Quick SARS-CoV-2 rRT-PCR Kit is only for use under the Food and Drug Administration’s Emergency Use Authorization.
Epigentek Inc CoviDrop SARS-CoV-2 Targeted Proprotein Convertase Activity/Inhibition Assay Kit (96 Assays)
For high throughput measurement of SARS-CoV-2 proprotein convertase cleavage inhibition from human samples
Epigentek Inc SeroFlash SARS-CoV-2 Neutralizing Antibody Assay Fast Kit (96 Assays)
Detect and quantitatively measure SARS-CoV-2 neutralizing antibody from various human samples
Epigentek Inc CoviDrop SARS-CoV-2 Targeted Proprotein Convertase Activity/Inhibition Assay Kit (48 Assays)
For high throughput measurement of SARS-CoV-2 proprotein convertase cleavage inhibition from human samples
Cayman Chemical SARSCoV2 B 1 1 7 SpIke Reag
An imidazoline receptor agonist selectively binds to imidazoline I1 and -I2 receptors over a2-ARs (IC50s 0.034 0.026 and 15 UM respectively) reduces complete Freund’s adjuvant-induced thermal and mechanical hyperalgesia in rats at 10 or 17.8 mg/kg decreases the latency to seizure onset and increases the percentage of animals with grade V seizures to a greater extent in female than male mice reverses cognitive deficits in the 5XFAD transgenic mouse model of Alzheimer’s disease at 5 mg/kg
Cayman Chemical SARS-CoV-2 Main Protease Enzy
An inducer of calcium influx enhances EV release from mBMDCs at 10 UM increases surface levels of CD86 and CD80 on mBMDCs at 10 UM an effect that can be blocked by BTP2 and increases CD86 and CD80 levels on mBMDC-derived EVs
Revvity Health Sciences Inc AlphaLISA SARS-CoV2 S1 / ACE2 Binding Kit, 500 Assay Points
AlphaLISA SARS-CoV2 S1 / ACE2 Binding Kit, 500 Assay Points
Cayman Chemical SARS-CoV-2 nsp8recombInt 100ug
A mitochondrial complex I inhibitor selective for complex I inhibiting it by 77.6 over complex III which it inhibits by 28.1 and complexes II and IV which it does not inhibit at 1 UM selectively reduces viability of H460 NCI H441 and trametinib-resistant A549 cells (IC50s 10.6 29.7 and 15.1 nM respectively) which all display high levels of oxidative phosphorylation over NCI H358 cells (IC50 10000 nM) which display low levels of oxidative phosphorylation and non-cancerous HPNE and MRC-5 cells (IC50s 10000 nM for both) reduces tumor volume in an H460 mouse xenograft model at 30 mg/kg twice per day has an additive effect on trametinib-induced tumor growth reduction
Cayman Chemical SARS-CoV-2 nsp7recombInt 100ug
A clickable RNA pseudoknot binder has been used in the synthesis of PINAD molecules for the degradation of SARS-CoV-2 RNA
Cayman Chemical SARS-CoV-2humn nutralIzI 100ug
A synthetic peptide corresponding to an integrin cell adhesion sequence a component of radioligands and peptidomimetics that have been used in the study of integrin expression and activity in vivo